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Description Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. It was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. Baclofen …
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