Chemotherapeutic Agents

Paclitaxel – Interactions and Overdose

Background Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as an intravenous solution for injection and the newer formulation …

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Capecitabine – Dosage

Background Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. It is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. Properties and Characteristics of Capecitabine Drug class Antimetabolites, Antineoplastics, chemotherapeutic agents Brand Names Ecansya, Xeloda Synonyms Capecitabin, Capecitabina, …

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