Cyclobenzaprine – Mechanism of action, Uses, and Interactions

Background Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants – it differs from Amitriptyline by only a single double bond. Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for …

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Amitriptyline – Uses and Dose

What is Amitriptyline? Amitriptyline is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood. Amitriptyline is a prescription medicine used to treat symptoms of depression. Brand names of Amitriptyline Common brand names are Elavil, Endep, and Vanatrip Storage Recommended storage temperature: 2 – 8 °C. Keep in a …

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